【亚英体育】改变的基因导致人们完全感觉不到疼痛 - 亚英体育-官方网

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【亚英体育】改变的基因导致人们完全感觉不到疼痛

2020-10-04 00:40:01

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亚英体育官网

亚英体育在线|Altered gene leaves people totally painfree转变的基因造成人们几乎感觉将近疼痛Naturally occurring changes in a previously unstudied gene can prevent people from experiencing pain. And thats not good. It can leave them dangerously unaware of harm.如果先天大自然构成的基因再次发生自然性的转变,那么人类感觉疼痛能力将不会阻碍,造成他们意识将近损害,这样很危险性!Researchers presented the finding May 25 in Nature Genetics.5月25日研究者在大自然遗传学上提交了这篇报告。The genes name is PRDM12. Pain is the bodys way of signaling that something is wrong. Certain mutations- naturally occurring changes - in that gene keep people from feeling pain. Robbed of this warning, affected people may fail to protect themselves from unintentional injuries. Such injuries could range from skin burns or scratched eyes to missing digits.该基因叫作PRDM12,疼痛是身体意识危险性的信号。特定基因突变---大自然再次发生的转变---造成人类感觉将近疼痛。

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这一预警信号被劫持后,那些不受影响人将无法在无意识的损害中维护自己。这些损害还包括皮肤烧伤,被抓挠的眼睛,甚至还包括遗失的脚趾手指等等。

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However, there is some good news in the finding. Better understanding of how a mutated PRDM12 gene blocks pain might one day lead to better treatments for people who suffer from too much pain.但幸运地的是在这项调查中还有好消息,即更佳地理解变异的基因PRDM12是怎样制止疼痛也许某天会应用于到那些正在遭到很大伤痛的人身上。Its promising, but theres a long way to go, says Simon Halegoua. Hes a neuroscientist at Stony Brook University in New York who did not work on the new study.前途是光明的,但依然还有很长的路要回头,纽约石溪大学神经系统学家Simon Halegoua回应,但是他没参予到新的研究中。Scientists already knew that mutations in another gene caused a similar birth defect: this insensitivity to pain. In their new study, Geoff Woods of the University of Cambridge in England and his colleagues identified 11 families with 亚英体育在线mutated forms of the PRDM12 gene. The gene normally instructs cells on how to make a protein that helps pain-sensing nerve cells develop. These pain-warning nerve cells, or neurons, are called nociceptors (NO-see-SEP-terz). People born with some mutations to PRDM12 lack some nociceptor neurons that carry pain signals to the brain. The new study suggests You need PRDM12 present to grow your pain neurons, Woods says.科学家早已告诉另一个基因突变不会引发类似于的先天缺失:感觉疼痛幼稚性,在他们的新研究中,英国剑桥大学的Geoff Woods和他的同事对11家家人的PRDM12基因变异形式展开了检验。基因一般来说不会提示细胞生产量蛋白质来协助触痛神经细胞发育。

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这些伴随疼痛的神经细胞,也叫神经元,被称作损害感受器。一些天生PRDM12基因突变的人缺少能将疼痛信号传输给大脑的损害感受器神即经元。Woods回应新的研究证明人们必须PRDM12来助长其疼痛神经原。|亚英体育在线。

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